Description
Mathematical and computational models in biological science enable the simulation of simple to complex biological processes, disease progression , mechanisms and dynamics, and distribution of drugs in tissues and organs while in biological engineering to model bioreactors/fermenters, growth kinetics and diffusion and separation processes. The models could be a set of ordinary or partial differential equations, derived from first principles with several assumptions. In this workshop modelling and simulation of various biological science and engineering problems will be discussed which will include reaction/cell growth kinetics, diffusion process in biofilm, predator – prey models, pharmacokinetics , bioreactor and chromatography.
A free downloadable ODE solver will be demonstrated to solve the various problems.
Profile of the Instructor
Dr Mukesh Doble, Prof Emeritus (Retd), IIT Madras and Director, Theevanam Additives & Nutraceuts p ltd (IITM Res Park), Distinguished Professor at Saveetha Dental College and Hospitals. Areas of expertise are Biomaterials, Drug design, Bioprocess and Biostatistics. Dr Mukesh holds B. Tech and M. Tech degrees in Chemical Engineering (IIT, Madras) , and Ph. D. from University of Aston, UK and Postdoctoral from Cambridge, U.K., and Texas A&M, U.S.A. He worked for 25 years in Chemical and Polymer Industries and then 20 years in Department of Biotechnology, IITMadras. Author of 380 papers,10 books, and 17 patents Currently has a start up , 4 MOOCS video courses in NPTEL and Swayam. Recipient of “Excellence in Basic Research” Award from Indian Institute of Chemical Engineers and National Award for Technology Innovation in Plastic Processing Industry, Govt of India. Listed as top 2% of scientist in the world (2022/2023/2024) as compiled by Stanford University, USA
(https://www.scopus.com/authid/detail.uri?authorId=20734150400)
Module Details
Day – 1
Module Name :
Reaction kinetics , Cell growth , Biofilm diffusion , Predator prey model , Stability analysis
Day 2 :
Module Name :
Pharmaco kinetics , Bioreactor stability , -Chromatography , Literature examples .
Concepts Covered :
Modelling of biological processes using ODE, difference- differential equations, stability analysis, eigen values
Learning Outcomes:
Learn to model various biological processes and use a ODE solver to simulate the system.
Certification
Attending the session and taking up the Final Quiz is the mandatory criteria for Certification
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