Prof. Debabrata Maiti is an Indian scientist specializing in organometallic chemistry and bioinspired catalysis and serving as a Professor of Chemistry at the Indian Institute of Technology Bombay, Mumbai. He was awarded the Shanti Swarup Bhatnagar Prize, the prestigious Indian national award for excellence in scientific research, for Chemical Sciences for the year 2022 for his significant contributions to developing transition metal catalysis for transforming organic molecules to prepare value-added materials by site- selective functionalization, leading impact on agrochemicals and pharmaceuticals industry.
Day 1 - Session Details
MODULE – 1 : Cross-coupling : 1 & 2
Concepts Covered:
Initial idea about cross-coupling reaction
C-C bond formation for agrochemicals and pharmaceutical synthesis.
Learning Outcomes
Students get a first idea of cross-coupling and C-C bond formation for agrochemicals and pharmaceutical synthesis
MODULE – 2 : Cross-coupling : 3 & 4
Concepts Covered:
3 & 4: Suzuki- Miyaura Coupling reaction in the industial scale drug developement
Learning Outcomes
Students get a first idea of Suzuki-Miyaura Coupling reaction in the industrial scale drug development
MODULE – 3 : Cross-coupling : 5 & 6
Concepts Covered:
Negishi Coupling for agro- and pharma- chemicals synthesis
Kumada-Cross Coupling reaction for drug synthesis
Learning Outcomes
Students get a first idea Negishi Coupling for agro- and pharma- chemicals synthesis & Kumada-Cross Coupling reaction for drug synthesis
MODULE – 4 : Cross-coupling : 7 & 8
Concepts Covered:
Stille Coupling & Sonogashira Coupling reaction
Hayashi-Miyaura Coupling & Tsuji- Trost reaction for using the industrial scale synthesis agrochemicals and pharmaceuticals
Learning Outcomes :
Students get a first idea Stille Coupling; Sonogashira Coupling reaction; Hayashi- Miyaura Coupling & Tsuji-Trost reaction for using the industrial scale synthesis agrochemicals and pharmaceuticals
Day 2 - Session Details
MODULE – 1 : Cross-coupling : 9 & 10
Concepts Covered:
Olefin Metathesis in the development of bio-active molecules
Pauson-Khand Reaction use for synthesis of natural products
Learning Outcomes
Students get a first idea Olefin Metathesis in the development of bio-active molecules & Pauson-Khand Reaction use for synthesis of natural products
Students get a first idea Other Transition Metal- Mediated Couplings for C-C Bond Formation
MODULE – 3 : Cross-coupling : 13 & 14
Concepts Covered:
Buchwald- Hartwig Amination (natural product synthesis in industrial scale)
Ullmann Ether Synthesis (C-O Bond Formation)
Learning Outcomes
Students get a first idea Carbon-Heteroatom Bond Formation: Buchwald-Hartwig Amination (natural product synthesis in industrial scale) & Ullmann Ether Synthesis (C-O Bond Formation)
MODULE – 4 : Cross-coupling : 15
Concepts Covered:
Summaries of the all reactions in the synthesis of pharmaceuticals.
Learning Outcomes :
Students get a first idea Summaries of the all reactions in the synthesis of pharmaceuticals.
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