Introduction to Synthetic Biology

Participants who want to register are requested to take the screenings first, link for which is given under the “Eligibility & Fees and Screenings” tab


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SKU: IIT Madras | Dates: 2nd - 15th March, 2023 Categories: ,


Mode of workshop:  HYBRID


Synthetic Biology is about looking at biological systems through the lens and formalisms of engineering. This results in a phenomenal tool to gain fundamental insights into the functions and molecular basis of biological phenomena as well as in a suite of technologies for programming biological objects at user’s will, from cells to new materials. The course will address such a double-sided ability of SynBio (for understanding and for doing) along with its potential not only to transform the health & agricultural sectors but also moving the current oil-based industry into a sustainable bio-based economy. The Course (quite centred but not limited to microbial SynBio) will include the following blocks:
1. The roots of Synthetic Biology. SynBio vs Genetic engineering. The 3 foundational papers of the field. The jargon of SynBio: Parts, devices, systems, modules, chassis, orthogonality, retroactivity.
2. The gene expression flow and its synthetic variants. Alternative genetic codes. Metrology, standards and standardization. PoPS and RIPS. Automated DNA assembly and foundries
3. Genetic circuits, logic gates and logic networks. The CELLO system. Genome engineering. Plasmid and transposon vectors. Assembly standards. MAGE and its variants. Triplet recoding and whole genome Synthesis.
4. Genome editing: CRISPR tools, base editors. Gene therapies. Metabolic engineering. CAD of new pathways and multi-objective optimization. Biosensors & Therapeutic strains.
5. Merging rational engineering with evolution: heterotic computing, genetic sampling of solution spaces. Leveraging intracellular architecture. Socio-economic ramifications. SynBio and SDGs. Scaling-up and biomanufacturing. Biomaterials and Engineered living materials (ELM).
6. Biosafety, biosecurity & IP. Genetic firewalls, containment. Barcoding & watermarking genomes. Global SynBio-based environmental interventions. Programming HGT. The 10 top challenges. CO2 capture, Galenics, scaling-up. Gene drives.
7. Microbiome engineering. Metabolic division of labour. 3D design of microbial partnerships. Biofilm engineering. Medical and environmental probiotics. Thinking big: bionic architecture. Earth Terraforming. Towards a new partnership with Nature. SynBio-based art and architecture.
The Program will be complemented with a daily journal Club and presentations of students’ projects.


Session dates:  2nd – 15th March, 2023

Time:  9am to 5pm 

Last date of Registration:

Registration Deadline: February 17, 2023

Once registered, selected students will be intimated by e-mail.

Payment deadline: February 19, 2023

Profile of the Instructor(s)


Prof Victor De Lorenzo is a lead researcher within the Systems Biology Program at the Centro Nacional de Biotecnología (CSIC) in Madrid. His current research focus involves deep engineering of soil bacteria both as cell factories for industrial biotransformations and as agents for environmental bioremediation and valorisation of toxic waste. Other areas of research include environmental microbiology, metabolic engineering, Pseudomonas putida biology and biotechnology, gene expression regulation, synthetic (micro)biology, and global warming. Victor has published over 300 scientific publications in Microbial Biotechnology and Molecular Microbiology Journals. He was awarded the King Jaime I Prize to Environmental protection (2001).

Detailed Schedule

Eligibility & Fees and Screenings

Intended audience:


Fees  for the workshop:

Course fees:
Free For IITM students
₹10,000 + GST for in-person students       
₹5,000 + GST for online students       
 ₹18,000 + GST for industry – in person only



Please fill the form below as a part of screenings  for registering in this workshop. Once you are short listed to attend the workshop, you will be informed of the same.



After successful completion of the course, a participation certificate will be awarded to each participant.


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